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BABAK: Rozp. C. Akad. Cisare Frantiska Josefa, Trida II, Roenik X, Cislo I, 1901, and Archiv für die gesamte Physiologie, 89, 154 (1902). Cited in BENEDICT and TALBOT (1915).

BAER, H.: Zur Technik der Ruhe-Nüchtern-Umsatz-Bestimmung beim Säugling. J. Beeinflusst Somnifen diesen Umsatz? Z. Kinderheilkd., 47, 226 (1929).

BENEDICT, F.G.: Vital energetics, a study in comparative basal metabolism. Publication 503. Carnegie Institution of Washington, Washington, DC, 1938.

BENEDICT, F.G., TALBOT, F.B.: The Gaseous Metabolism of Infants. Carnegie Institution of Washington, Washington, DC, 1914.

BENEDICT, F.G., TALBOT, F.B.: The Physiology of the New-Born Infant. Carnegie Institution of Washington, Washington, DC, 1915.

BENEDICT, F.G., TALBOT, F.B.: Metabolism and Growth from Birth to Puberty, pp. 100-176. Carnegie Institution of Washington, Washington, DC, 1921.

BROOKE, O.G., COCKS, T., MARCH, Y.: Resting metabolic rate in malnourished babies in relation to total body potassium. Acta Paediatr. Scand., 63, 817-825 (1974).

BRUCK, K.: Temperature regulation in the newborn infant. Biol. Neonate, 3, 65-119 (1961).

BUTTE, N.F., SMITH, E.O., GARZA, C.: Energy utilization of breast-fed and formula-fed infants. Am. J. Clin. Nutr., 51, 350-358 (1990)

BUTTE, N.F., WONG, W.W., GARZA, C., KLEIN, P.D.: Energy expenditure and growth of breast-fed and formula-fed infants. FASEB J., 3, A5936 (1989).

CLAGETT, D.D., HATHAWAY, M.L.: Basal metabolism of normal infants from three to fifteen months of age. Am. J. Dis. Child., 62, 967-980 (1941).

DUBOIS, E.F.: Basal metabolism in health and disease. Lea and Febiger, Philadelphia, PA, 1936.

DURNIN, J.V.G.A., PASSMORE, R.: Energy, Work and Leisure. Heinemann, London, 1967.

FAO/WHO/UNU: Energy and protein requirements. Report of a joint FAO/WHO/UNU ad hoc expert consultation. Technical Report Series No. 724. WHO, Geneva, 1985.

FLEMING, G.B., HUTCHISON, H.S.: A study of the metabolism in the undernourished infant. Q. J. Med. (Oxford), 17, 339-357 (1924).

FORSTER: Amtlicher Bericht der 50. Versammlung Deutscher Naturforscher und Aerzte, p. 355. München, 1877. Cited in BENEDICT and TALBOT (1915).

GRANDE, F.: Energy expenditure of organs and tissues. In: Assessment of Energy Metabolism in Health and Disease, pp. 88-92, J.M. KINNEY, (Ed.). Ross Laboratories, Columbus, OH, 1980.

HARRIS, J.A., BENEDICT, F.G.: A biometric study of basal metabolism in man. Publication 279. Carnegie Institution of Washington, Washington, DC, 1919.

HOLLIDAY, M.A.: Metabolic rate and organ size during growth from infancy to maturity and during late gestation and early infancy. Pediatrics, 47,169-179 (1971).

HOLLIDAY, M.A.: Body composition and energy needs during growth. In: Human Growth: A Comprehensive Treatise, 2nd ea., pp. 101-117, F. FALKNER, J.M. TANNER (Eds.), Plenum Press, New York, NY, 1986.

HOLLIDAY, M.A., POTTER, D., JARRAH, A., BEARG, S.: Relation of metabolic rate to body weight and organ size. A review. Pediatr. Res., 1, 185-195 (1967).

HOWLAND, J.: Proc. Soc. Exper. Biol. Med., 1911, 8, 63; Hoppe-Seyler's Zeitschr. Physiol. Chem. 1911, 74, 1. (These experiments were published in detail and the results fully discussed by Howland in the Trans. 15th Int. Congress on Hygiene and Demography, ii, 438, Washington, DC, 1913.

JANET, H., BOCHET, M.: Sur le métabolisme basal du nourrisson. Bull. Soc. Pediatr. (Paris), 31, 359 (1933).

KAIRAM, R., SCHULZE, K., KOENIGSBERGER, M., JAMES, L.S.: The effects of changing sleep state on autonomic functions in the newborn. Pediatr. Res., 13, 498 (1979).

KARLBERG, P.: Determinations of standard energy metabolism (basal metabolism) in normal infants. Acta Paediatr., 41, Suppl. 89 (1952).

KEYS, A., BROZEK, J., HENSCHEL, A., MICKELSEN, O., TAYLOR, H.L.: The Biology of Human Starvation. University of Minnesota Press, Minneapolis, MN, 1950.

KLEIBER, M.: Body size and metabolic rate. Physiol. Rev., 27, 511-541 (1947).

KLEIBER, M.: Body size and metabolic rate. In: The Fire of Life, pp. 179-222. Robert E. Krieger Publishing Company, Huntington, New York, 1975.

KRIEGER, I., WHITTEN, C.F.: Energy metabolism in infants with growth failure due to maternal deprivation, undernutrition or causes unknown. 2. Relationship between nitrogen balance, weight gain and postprandial excess of heat production. J. Pediatr., 75, 374-379 (1969).

LANGLOIS: Journ. de l'Anat. et de Physiol., 23, 400 (1887). Cited in BENEDICT and TALBOT (1915).

LEE, V.A., ILIFF, A.: The energy metabolism of infants and young children during postprandial sleep. Pediatrics, 18, 739-748 (1956).

LEVINE, S.Z., WILSON, J.R., BERLINER, F., RIVKIN, H.: The respiratory metabolism in infancy and in childhood. VI. The specific dynamic action of foods in normal infants. Am. J. Dis. Child., 33, 722-731 (1927).

LEVINE, S.Z., WILSON, J.R., GOTTSCHALL, G.: The respiratory metabolism in infancy and in childhood. VIII. The respiratory exchange in marasmus: basal metabolism. Am. J. Dis. Child., 35, 615-630 (1928).

LEVINE, S.Z., MARPLES, E.: The respiratory metabolism in infancy and in childhood. Am. J. Dis. Child., 41, 1332-1346 (1931).

MENSI: Giorn. d. R. Accad. di Med. di Torino, 57, 301 (1894). Cited in BENEDICT and TALBOT (1914).

MESTYAN, J., JARAI, I., FEKETE, M.: The total energy expenditure and its components in preterm infants maintained under different nursing and environmental conditions. Pediatr. Res., 2,161-171 (1968).

MONTGOMERY, R.D.: Changes in the basal metabolic rate of the malnourished infant and their relation to body composition. J. Clin. Invest., 41,1653-1663 (1962).

MURLIN, J.R. HOOBLER, B.R.: The energy metabolism of ten hospital children. Am. J. Dis. Child., 9, 81-119 (1915).

MURLIN, J.R., CONKLIN, R.E., MARSH M.E.: Energy metabolism of normal newborn babies with special reference to the influence of food and of crying. Am. J. Dis. Child., 29, 1-28 (1925).

PARRA, A., GARZA, C., GARZA, Y., SARAVIA, J.L., HAZLEWOOD, C.F., NICHOLS, B.L.: Changes in growth hormone, insulin, and thyroxine values, and in energy metabolism of marasmic infants. J. Pediatr., 82, 133-142 (1973).

POPPI: Il ricambio materiale e il ricambio respiratorio nell'atrofia infantile. Bologna, Italy, 1900.

RICHET: Archives de Physiol. norm. et path., 15, 3d ser., 237 (1885). Cited in BENEDICT and TALBOT (1914).

RUBNER, M.: Über den Einfluss der Körpergrösse auf Stoff- und Kraftwechsel. Z. Biol., 19, 534 (1883).

RUBNER, HEUBNER: Z. Biol., 36 (1898). Cited in BENEDICT and TALBOT (1914).

SASSIN, J.F., PARKER, D.C., MACE, J.W., GOTLIN, W.R., JOHNSON, L.C., ROSSMAN, L.G.: Human growth hormone release: relation to slow-wave sleep and sleep-waking cycles. Science, 165, 513-515 (1969).

SCHERER: Jahrb. Kinderheilkd., N.F., 43, 471 (1896).

SCHLOSSMANN, OPPENHEIMER, MURSCHHAUSER: Biochem. Z., 14, 385 (1908). Cited in BENEDICT and TALBOT (1914).

SCHOFIELD, W.N.: Predicting basal metabolic rate, new standards and review of previous work. Hum. Nutr. Clin. Nutr., 39C, Suppl. 1, 5-41 (1985).

SCOPES, J.W., AHMED, I.: Minimal rates of oxygen consumption in sick and premature infants. Arch. Dis. Child., 41, 407-416 (1966).

SINCLAIR, J.C., SILVERMAN, W.A.: Relative hypermetabolism in undergrown neonates. Lancet, 2, 49 (1964).

SINCLAIR, J.C., SCOPES J.W., SILVERMAN, W.A.: Metabolic reference standards for the neonate. Pediatrics, 39, 724-732 (1967).

TALBOT, F.B.: Basal metabolism of children. Physiol. Rev., 5, 477-517 (1925).

TALBOT, F.B.: Basal metabolism standards for children. Am. J. Dis. Child., 55, 455459 (1938)

WATERLOW, J.C., ALLEYNE, G.A.O.: Protein malnutrition in children: advances in knowledge in the last ten years. Adv. Protein Chem., 25,117-235 (1971).

Discussion (summarized by B. Schürch)

The BMR of a 3-year-old child is more than 50% of an adult's, yet its weight is only around 20% of an adult's; can all of this be explained in terms of organ growth? The question cannot be answered definitively, but the fact that, in young animals, muscle has a higher BMR per weight than in old animals would suggest that other factors play a role as well.

Changes in sleeping metabolic rate occur a few minutes before the change in sleep state (REM, non-REM); hormonal changes seem to be responsible for this phenomenon.

In Butte's studies, infants with a higher sleeping metabolic rate generally also had higher activity scores.

The SMR of an infant can be altered by 50% by ambient temperature; controlling ambient temperature is therefore important in the measurement of sleeping metabolic rate in infants.

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