TABLE 6 Coverage in the follow-up cohorts by migration status
Village type |
Migrants |
Nonmigrants |
||||
T |
P |
% |
T |
P |
% |
|
Fresco¹ |
||||||
Santo Domingo |
212 |
79 |
37.3 |
382 |
332 |
86.9 |
Espiritu Santo |
138 |
66 |
47.8 |
285 |
256 |
89.8 |
Atole² |
||||||
Conacaste |
201 |
80 |
39.8 |
474 |
408 |
86.1 |
San Juan |
176 |
71 |
40.3 |
301 |
282 |
93.7 |
Supplemented Combined |
727 |
296 |
40.7 |
1442 |
1278 |
88.6 |
Comparison |
||||||
Subinal |
61 |
28 |
45.9 |
177 |
137 |
77.4 |
Las Ovejas |
98 |
44 |
44.9 |
288 |
236 |
81.9 |
El Caulote |
76 |
33 |
43.4 |
229 |
168 |
73.4 |
Comparison Combined |
235 |
105 |
44.7 |
694 |
541 |
78.0 |
ALL VILLAGES |
962 |
401 |
41.7 |
2136 |
1819 |
85.2 |
¹ Large Fresco village, Santo Domingo; small Fresco village, Espiritu Santo.
² Large Atole village, Conacaste; small Atole village, San Juan; T. target sample; P. participants; %, coverage.
Table 6 presents coverage rates by migration status. Coverage rates differed between supplemented and comparison villages; among nonmigrant subjects, coverage rates were ~10% greater in supplemented (88.6%) than in comparison villages (78.0%.). This is probably the result of the good rapport built by INCAP during the 9 y of the longitudinal study. On the other hand, coverage for migrants was slightly less in supplemented (40.7%) than comparison villages (44.7%). This may be due to differences in how the target sample was defined in supplemented and comparison villages. The target sample of migrants in the comparison villages was identified using information available in the 1987 census. Therefore, only adolescent migrants whose families were still living in the villages at the time of the follow-up census were selected. In contrast, in the supplemented villages, follow-up cohorts whose entire families had migrated before the beginning of the follow-up study also were selected, using records from the longitudinal study. Some of these migrant families were located using information provided by neighbors and relatives; however, as a result of the absence of parents or close relatives, follow-up cohorts belonging to these families were much more difficult to locate than migrants whose families were still living in the villages.
Coverage rates for migrants were overall much lower than those for nonmigrants because of the difficulty of locating migrants and because data collection in migrants was restricted to those living in Guatemala City and two provincial cities. The decision to focus on these locations was based on resource restrictions and the fact that information available at the beginning of the study indicated that ~64% of the subjects for whom locations were known lived in one of these three cities. Coverage for migrants known to have moved to these three cities was 62%. For the entire migrant sample, coverage was 42% (Table 6).
Coverage rates for females were greater in both migrants and nonmigrants. In migrants, coverage rates were 45.6% and 36.9% for females and males respectively; these patterns were similar in supplemented (females: 176/394 = 44.75% and males: 120/333 = 36.0%) and comparison villages (females: 65/134 = 48.5% and males: 40/101 = 39.6%). In nonmigrants, coverage for females was 89.7% and for males 81.2%. Coverage rates were greater in females in supplemented villages (females: 623/666 = 93.5% and males: 655/776 = 84.4%) as well as in comparison villages (females:278/339=82.0% and males:263/255=74.1%).
TABLE 7 Percent coverage in the follow-up exhorts by birth cohorts and gender
Cohorts¹ Village type |
Females |
Males |
||||||
I |
II |
III |
IV |
I |
II |
III |
IV |
|
Fresco² |
||||||||
Santo Domingo |
84.1 |
73.0 |
56.4 |
68.8 |
82.3 |
70.9 |
61.5 |
50.0 |
Espíritu Santo |
90.4 |
74.4 |
65.9 |
69.2 |
87.5 |
77.3 |
55.8 |
62.1 |
Atole³ |
||||||||
Conacaste |
84.8 |
74.1 |
79.4 |
81.4 |
87.5 |
65.7 |
55.8 |
53.8 |
San Juan |
76.3 |
79.0 |
67.9 |
67.9 |
90.8 |
74.0 |
58.5 |
57.1 |
Supplemented Combined |
83.8 |
75.1 |
67.9 |
73.1 |
87.1 |
71.2 |
60.3 |
54.5 |
Comparison |
||||||||
Subinal |
89.2 |
83.3 |
54.2 |
58.3 |
90.9 |
67.4 |
46.7 |
42.9 |
Las Ovejas |
83.8 |
81.2 |
64.7 |
66.0 |
85.7 |
81.4 |
61.9 |
49.0 |
El Caulote |
87.8 |
76.6 |
55.2 |
47.6 |
91.7 |
70.6 |
38.5 |
42.4 |
Comparison Combined |
87.0 |
80.4 |
58.6 |
57.5 |
88.8 |
73.7 |
51.8 |
45.5 |
ALL VILLAGES |
84.8 |
76.6 |
65.2 |
67.5 |
87.6 |
71.9 |
57.9 |
51.2 |
¹ See Table 3 for cohort definitions. Values are percentages.
² Large Fresco village, Santo Domingo; small Fresco village, Espíritu Santo.
³ Large Atole village, Conacaste; small Atole village, San Juan.
Subjects were classified into four birth cohorts according to ages of exposure to supplementation (Table 3). Table 7 presents coverage rates by cohort and village. In general, Cohort I has the highest coverage rates, followed by Cohort II and finally by Cohorts III and IV. Younger subjects may have had more time to participate in the various tests and interviews than older subjects.
Table 8 presents coverage rates for the different study domains by village type. Coverage rates were ~ 70% for most domains. The low coverage for blood collection deserves comment. Interviews of subjects who had refused to participate and of their families revealed that anxiety related to blood collection was one of the principal reasons for nonparticipation. Some subjects felt that the very small amount of blood collected (5 mL) was very large relative to the total blood volume in an adult. In one village, there were rumors that the blood was being sold. To remedy the situation, subjects were informed that blood collection was not essential for participation in the rest of the tests, measurements and interviews. In addition, subjects were reminded that blood samples also were used for the diagnosis of anemia, with treatment provided when necessary. Subsequently the refusal rate declined, though refusals to provide a blood sample among participants in the study remained high.
Table 8 also presents coverage rates for the different study domains in the comparison villages. Coverage rates were slightly less than found in the supplemented villages, but follow the same patterns. For the work capacity test, more subjects than originally planned were examined in comparison villages (see Haas et al. 1995).
Coverage rates for anthropometric measurements of parents of the follow-up sample was 82.4%, with no difference between supplemented (809/979 = 82.6%) and comparison villages (386/472 = 81.8%). Similar coverage rates were obtained for the life history of mothers of the follow-up samples (82.7%), with similar coverage rates for supplemented (452/543 = 83.2%) and comparison villages (207/253 = 81.8%). In contrast, coverage of the income and wealth questionnaire applied to heads of households was lower (62.0%), with rates being similar in supplemented (62.5%) and comparison villages (60.7%). The low coverage rates for the income and wealth interviews were due in part to the long time required to obtain the information and the fact that most of the heads of households worked in agriculture and were away during most of the day.
TABLE 8 Coverage rates by study domain and village type for the follow-up cohorts
Study area
|
Supplemented villages |
Comparison villages |
||||
T |
P |
% |
T |
P |
% |
|
Anthropometry |
2169 |
1554 |
71.7 |
929 |
633 |
68.1 |
Medical Exam |
2169 |
1543 |
71.1 |
929 |
630 |
67.8 |
Hand-wrist x-rays |
1149 |
920 |
80.1 |
459 |
337 |
73.4 |
Blood sample |
2169 |
1196 |
55.1 |
929 |
425 |
45.7 |
Psychology tests Functional
competence and intelligence |
1897 |
1367 |
72.1 |
766 |
532 |
69.5 |
Information processing |
1897 |
1331 |
70.2 |
766 |
521 |
68.0 |
Life history |
||||||
Males |
1109 |
742 |
66.9 |
456 |
282 |
61.8 |
Females |
1060 |
730 |
68.9 |
473 |
311 |
65.8 |
Work capacity subsample |
388 |
361 |
93.0 |
152 |
178 |
100.0¹ |
T. target sample; P. participants, %, coverage.
¹ More subjects were examined than originally planned.
Concluding remarks
Full details about design and methods, such as contained in this article, are often not readily available in the literature. The INCAP longitudinal and follow-up studies are among the most important sources of information from developing countries about child growth, development and nutrition and it is likely that there will be continued analyses of these data for years to come. It is important to have a faithful record of the design, objectives, methods and procedures, particularly for the benefit of analysts who may not have been directly involved with the studies.